Knowledge center

Publications

  • Side-by-Side Economic Process Model for the Comparison and Evaluation of Magnetic Bead-Based Processes and Legacy Process for the Manufacturing of Monoclonal Antibodies

    Brechmann NA, Stamatis C, Farid SS, Chotteau V, Eriksson K

    Processes. 2024;12(11):2563

  • Detection of synthetic analogues of insulin-like growth factor 1 in different biological fluids by liquid chromatography quadrupole time-of-flight mass spectrometry: comparison of different immunoaffinity protocols

    Monica Mazzarino, Isabella Melis, Edoardo Quaresima and Francesco Botrè

    Springer Nature, Volume 415, pages 6117–6131 (2023)

  • Accurate determination of the milk protein allergen β-lactoglobulin by on-line aptamer affinity solid-phase extraction capillary electrophoresis-mass spectrometry

    María Vergara-Barberán, Ernesto Francisco Simó-Alfonso, José Manuel Herrero-Martínez, Fernando Benavente

    Talanta, Volume 259, 1 July 2023, 124542

  • Optimization of medium with perfusion microbioreactors for high density CHO cell cultures at very low renewal rate aided by design of experiments

    Schwarz H, Lee K, Castan A, Chotteau V

    Biotechnology and Bioengineering 2023, 120 (9), 2523-2541

  • Determination of a lectin protein allergen in food by on-line aptamer affinity solid-phase extraction capillary electrophoresis-mass spectrometry

    María Vergara-Barberán, Ernesto Francisco Simó-Alfonso, José Manuel Herrero-Martínez, Fernando Benavente

    Microchemical Journal, Volume 190, July 2023, 108746

  • Monitoring of amino acids and antibody N-glycosylation in high cell density perfusion culture based on Raman-spectroscopy

    Schwarz H, Mäkinen ME, Castan A, Chotteau V

    Biochemical Engineering 2022, 182, 108426

  • On-line Coupling of Aptamer Affinity Solid-Phase Extraction and Immobilized Enzyme Microreactor Capillary Electrophoresis-Mass Spectrometry for the Sensitive Targeted Bottom-Up Analysis of Protein Biomarkers

    Hiba Salim, Roger Pero-Gascon, Estela Giménez and Fernando Benavente*

    Analytical Chemistry, Vol 94 / Issue 19 (2022)

  • Proof-of-Concept of a Novel Cell Separation Technology Using Magnetic Agarose-Based Beads

    Brechmann NA, Jansson M, Hägg A, Hicks R, Hyllner J, Eriksson K, Chotteau V

    Magnetochemistry 2022, 8 (3), 34

  • Specific and rapid reverse assaying protocol for detection and antimicrobial susceptibility testing of Pseudomonas aeruginosa based on dual molecular recognition

    Yong He, Hang Zhao, Yuanwen Liu & He Zhou

    Scientific Reports volume 11, Article number: 11101 (2021)

  • Control of IgG glycosylation in CHO cell perfusion cultures by GReBA mathematical model supported by a novel trageted feed, TAFE

    Zhang L, Schwarz H, Wang M, Castan A, Hjalmarsson H, Chotteau V

    Metabolic Engineering 2021, 65, 135-145

  • Antibody capture process based on magnetic beads from very high cell density suspension

    Brechmann NA, Schwarz H, Eriksson PO, Eriksson K, Shokri A, Chotteau V

    Biotechnology and Bioengineering 2021, 118, 3499-3510

  • Probabilistic model by Bayesian network for the prediction of antibody glycosylation in perfusion and fed-batch cell cultures

    Zhang L, Wang M, Castan A, Hjalmarsson H, Chotteau V

    Metabolic Engineering 2021, 118 (9), 3447-3459

  • Comparison of magnetic bead surface functionalities for the immunopurification of growth hormone-releasing hormones prior to liquid chromatography-high resolution mass spectrometry

    Laura Pont, Élida Alechaga, Alejandro Terrero, Núria Monfort, Rosa Ventura

    Journal of Chromatography A, Volume 1631, 8 November 2020, 461548

  • Glycan Residues Balance Analysis – GReBA: A novel model for the N-linked glycosylation of IgG prodcuded by CHO cells

    Zhang L, Wang M, Castan A, Stevenson J, Chatzissavidou N, Hjalmarsson H, Vilaplana F, Chotteau V

    Metabolic Engineering 2020, 57, 118-128

  • An inductively coupled plasma-mass spectrometry (ICP-MS) linked immunoassay by means of iodinated antibodies for transferrin quantitative analysis in breast cancer cell lines

    F. J. Alonso-García, E. Blanco-González, M. Montes-Bayón

    Talanta 194 (2019) 336–342

  • Combined effects of glycosylation precursors and lactate on the glycoprofil of IgG produced by CHO cells

    Zhang L, Castan A, Stevenson J, Chatzissavidou N, Vilaplana F, Chotteau V

    Journal of Biotechnology 2019, 289, 71-79

  • Pilot-scale process for magnetic bead purification of antibodies directly from non-clarified CHO cell culture

    Brechmann NA, Eriksson PO, Eriksson K, Oscarsson S, Buijs J, Shokri A, Hjälm G, Chotteau V

    Biotechnology Progress 2019, 35, 2775

  • A rapid and highly specific immunofluorescence method to detect Escherichia coli O157:H7 in infected meat samples

    Balakrishnan B, Barizuddin S, Wuliji T, El-Dweik M

    International Journal of Food Microbiology 231 (2016) 54–62

  • Ultra-sensitive chemiluminescent detection of Staphylococcus aureus based on competitive binding of Staphylococcus protein A-modified magnetic beads to immunoglobulin G

    J. Xiong, W. Wang. Y. Zhou, W. Kong, Z. Wang, Z. Fu

    Microchim Acta (2016) 183:1507–1512

  • Analysis of serum transthyretin by on-line immunoaffinity solid-phase extraction capillary electrophoresis mass spectrometry using magnetic beads

    Peró-Gascón, R., Pont, L., Benavente, F., Barbosa, J., Sanz-Nebot, V.

    Electrophoresis 2016, 37, 1220-1231

  • Highly specific and rapid immuno-fluorescent visualization and detection of E. coli O104:H4 with protein-A coated magnetic beads based LST-MUG assay

    Barizuddin, S., Balakrishnan,B., Stringer, R. C., Dweik, M

    J. Microbiol. Methods 2015, 115, 27-33

  • Label-free bead-based metallothionein electrochemical immunosensor

    Nejdl, L., Nguyen, H. V., Richtera, L., Krizkova, S., Guran, R., Masarik, M., Hynek, D., Heger Z., Lundberg, K., Eriksson, K., Adam, V., Kizek, R.

    Electrophoresis 2015, 36, 1894–1904