Applications
Monoclonal antibodies
Monoclonal antibody manufacturing faces many challenges, especially during clarification. High cell densities often lead to insufficient removal during centrifugation, clog filters and/or add steps that reduces yields and increase costs.
Magnetic separation solves these problems by combining clarification and product capture in one streamlined step, replacing centrifugation, filtration, and affinity column-chromatography while boosting yields, throughput, and cost efficiency.
Cell Therapy
Cell therapies, especially allogeneic hiPSC-based therapies, show promise for severe diseases due to self-renewal, differentiation, and ethical advantages. However, their complex manufacturing process present significant barriers that restrict patient access, including high costs and scale-up challenges as well as ensuring patient safety by removal of undifferentiated cells.
Magnetic separation streamlines cell isolation, improving efficiency and scalability.
SPRI-Based Cleanup & Library Prep
High-quality sequencing starts with high-quality DNA. Inconsistent SPRI bead cleanup, slow magnetic separation, and bead sticking create variability, sample loss, and bottlenecks that compromise library preparation. MAGic™SPRI HMW combines superior magnetisation with precise solid-phase reversible immobilisation (SPRI) technology to deliver fast, consistent DNA cleanup and fragment size selection from 100 bp to 5 kb in a single, automation-ready bead solution.