MAGic™Beads mAb

420,0025.200,00

Description

Magnetic resins
MAGic bioprocessing provides magnetic agarose-based resins that are used to recover biologics or other biomolecules directly from crude sample mixtures eliminating the need of clarification. Our MAGicBeads are highly porous which provides a large available surface area (50m2/ml) resulting in exceptional high binding capacities, similar to column resins. The beads are also strongly magnetized (40emu/g) and stable due to our proprietary manufacturing method which provides consistent and fast magnetic separation even in large sample volumes (litres).

Our MAGicBeads are also compatible with robotic system such as the KingFisher™ Flex unit (Thermo Fisher) allowing the use of our beads in automatic setups for high-throughput screening.

Super-paramagnetic porous beads coupled with an alkali resistant protein A ligand. Optimized for purification of monoclonal antibodies directly from cell culture harvests, thus eliminating centrifugation or filtration, such as from hybridoma or CHO cells, where sanitization of beads with NaOH is desired between the uses. High binding capacity and fast magnetic response makes the beads suitable for separation even in large-volume samples.

  • Recover your mAb and skip centrifugation and filtration to remove cells.
  • Top performance binding capacity, up to 65mg IgG/ml of settled beads.
  • Ability to clean the beads between the purification cycles using 0.5M NaOH.
  • Stable and reusable for up to 100 times using 0.5M NaOH with 15min contact time.

Documents

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MSDS

MAGic Beads mAb

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USER MANUAL

MAGic Beads mAb

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APPLICATION NOTE

Static binding capacity

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APPLICATION NOTE

Non clarified approach

Applications
Our super-paramagnetic agarose beads, MAGic™Beads, are intended for purification from non-clarified cell culture broth, such as from hybridoma or CHO cells and from serum and ascites fluid samples. The magnetic beads, due to their high magnetization, are seamlessly scalable from high-throughput small scale screening to production scale. Our beads are fully integratable with commercial automated pipetting systens, such as the KingFisher instrument or Te-Mags™.

Contact us
For custom product sizes or specific solution to your purification needs please contact us via mail: info@magicbioprocessing.com

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